Psychological predictors of benzodiazepine discontinuation among older adults: Results from the PASSE 60.
Identifieur interne : 000125 ( Main/Exploration ); précédent : 000124; suivant : 000126Psychological predictors of benzodiazepine discontinuation among older adults: Results from the PASSE 60.
Auteurs : Arnaud Allary [Canada] ; Virginie Proulx-Tremblay [Canada] ; Claude Bélanger [Canada] ; Carol Hudon [Canada] ; André Marchand [Canada] ; Kieron O'Connor [Canada] ; Guilhème Pérodeau [Canada] ; Pasquale Roberge [Canada] ; Cara Tannenbaum [Canada] ; Helen-Maria Vasiliadis [Canada] ; Caroline Desrosiers [Canada] ; Diana Cruz-Santiago [Canada] ; Sébastien Grenier [Canada]Source :
- Addictive behaviors [ 1873-6327 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen (MeSH), Anxiété (MeSH), Auto-efficacité (MeSH), Benzodiazépines (effets indésirables), Benzodiazépines (usage thérapeutique), Déprescriptions (MeSH), Dépression (MeSH), Femelle (MeSH), Gestion de soi (MeSH), Humains (MeSH), Mâle (MeSH), Soutien social (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Syndrome de sevrage (psychologie), Thérapie cognitive (méthodes), Troubles de l'endormissement et du maintien du sommeil (MeSH).
- MESH :
- effets indésirables : Benzodiazépines.
- méthodes : Thérapie cognitive.
- psychologie : Syndrome de sevrage.
- usage thérapeutique : Benzodiazépines.
- Adulte d'âge moyen, Anxiété, Auto-efficacité, Déprescriptions, Dépression, Femelle, Gestion de soi, Humains, Mâle, Soutien social, Sujet âgé, Sujet âgé de 80 ans ou plus, Troubles de l'endormissement et du maintien du sommeil.
English descriptors
- KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Anxiety (MeSH), Benzodiazepines (adverse effects), Benzodiazepines (therapeutic use), Cognitive Behavioral Therapy (methods), Deprescriptions (MeSH), Depression (MeSH), Drug Tapering (methods), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Self Efficacy (MeSH), Self-Management (MeSH), Sleep Initiation and Maintenance Disorders (MeSH), Social Support (MeSH), Substance Withdrawal Syndrome (psychology).
- MESH :
- chemical , adverse effects : Benzodiazepines.
- chemical , therapeutic use : Benzodiazepines.
- methods : Cognitive Behavioral Therapy, Drug Tapering.
- psychology : Substance Withdrawal Syndrome.
- Aged, Aged, 80 and over, Anxiety, Deprescriptions, Depression, Female, Humans, Male, Middle Aged, Self Efficacy, Self-Management, Sleep Initiation and Maintenance Disorders, Social Support.
Abstract
BACKGROUND
Long-term benzodiazepine (BZD) use among seniors is mostly inappropriate and associated with adverse health outcomes. To prevent these consequences, withdrawal is crucial, yet knowledge is limited about what predicts BZD discontinuation. Until now, most studies have focused on sociodemographic and BZD intake factors as predictors while neglecting psychological factors. This research addresses this issue by studying how the intensity of depressive symptoms, social support satisfaction, self-perceived competence in the ability to withdraw, and overall quality of sleep predict discontinuation in long-term older consumers.
METHOD
Seventy-three participants aged 60 years and older were enrolled in this study. There were four time measures: before discontinuation (T1), after (T2), 3 months after (T3), and 12 months after (T4). Data were collected in the "Programme d'Aide du Succès au SEvrage" (PASSE-60+) study.
RESULTS
Social support satisfaction predicted discontinuation at T2 and T4. Self-perceived competence in the ability to withdraw and depressive symptoms predicted discontinuation at T4. This later prediction was counterintuitive; higher depressive symptoms at T1 were linked with higher discontinuation success. BZD intake factors (length of use and dose) were good predictors for short term discontinuation. Psychological factors were moderate predictors for short term and good predictors for long term discontinuation.
CONCLUSION
Psychological factors are good predictors of discontinuation and are better predictors than BZD intake factors of long-term discontinuation. Discontinuation programs should focus on social support and self-perceived competence to improve their efficacy. Further studies are needed to acquire a more complete picture of the psychological predictors of discontinuation success. ClinicalTrials.gov Identifier: NCT02281175.
DOI: 10.1016/j.addbeh.2019.106195
PubMed: 31838367
Affiliations:
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Faculté de médicine, Université de Montréal, Québec, Canada; Faculté de pharmacie, Université de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Faculté de médicine, Université de Montréal, Québec, Canada; Faculté de pharmacie, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Vasiliadis, Helen Maria" sort="Vasiliadis, Helen Maria" uniqKey="Vasiliadis H" first="Helen-Maria" last="Vasiliadis">Helen-Maria Vasiliadis</name><affiliation wicri:level="1"><nlm:affiliation>Faculté de médecine de l'Université de Sherbrooke, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Faculté de médecine de l'Université de Sherbrooke, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Desrosiers, Caroline" sort="Desrosiers, Caroline" uniqKey="Desrosiers C" first="Caroline" last="Desrosiers">Caroline Desrosiers</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Cruz Santiago, Diana" sort="Cruz Santiago, Diana" uniqKey="Cruz Santiago D" first="Diana" last="Cruz-Santiago">Diana Cruz-Santiago</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de médecine familiale et de médecine d'urgence, Université de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de médecine familiale et de médecine d'urgence, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Grenier, Sebastien" sort="Grenier, Sebastien" uniqKey="Grenier S" first="Sébastien" last="Grenier">Sébastien Grenier</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec, Canada. Electronic address: sebastien.grenier@umontreal.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31838367</idno><idno type="pmid">31838367</idno><idno type="doi">10.1016/j.addbeh.2019.106195</idno><idno type="wicri:Area/Main/Corpus">000278</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000278</idno><idno type="wicri:Area/Main/Curation">000278</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000278</idno><idno type="wicri:Area/Main/Exploration">000278</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Psychological predictors of benzodiazepine discontinuation among older adults: Results from the PASSE 60.</title><author><name sortKey="Allary, Arnaud" sort="Allary, Arnaud" uniqKey="Allary A" first="Arnaud" last="Allary">Arnaud Allary</name><affiliation wicri:level="4"><nlm:affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada; Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada; Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec</wicri:regionArea><orgName type="university">Université du Québec à Montréal</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Proulx Tremblay, Virginie" sort="Proulx Tremblay, Virginie" uniqKey="Proulx Tremblay V" first="Virginie" last="Proulx-Tremblay">Virginie Proulx-Tremblay</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Belanger, Claude" sort="Belanger, Claude" uniqKey="Belanger C" first="Claude" last="Bélanger">Claude Bélanger</name><affiliation wicri:level="4"><nlm:affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de psychologie, Université du Québec à Montréal (UQAM), Québec</wicri:regionArea><orgName type="university">Université du Québec à Montréal</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Hudon, Carol" sort="Hudon, Carol" uniqKey="Hudon C" first="Carol" last="Hudon">Carol Hudon</name><affiliation wicri:level="4"><nlm:affiliation>École de psychologie de l'Université Laval, Québec, Canada; Centre de recherche CERVO, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>École de psychologie de l'Université Laval, Québec, Canada; Centre de recherche CERVO, Québec</wicri:regionArea><orgName type="university">Université Laval</orgName><placeName><settlement type="city">Québec (ville)</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Marchand, Andre" sort="Marchand, Andre" uniqKey="Marchand A" first="André" last="Marchand">André Marchand</name><affiliation wicri:level="4"><nlm:affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de psychologie, Université du Québec à Montréal (UQAM), Québec</wicri:regionArea><orgName type="university">Université du Québec à Montréal</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="O Connor, Kieron" sort="O Connor, Kieron" uniqKey="O Connor K" first="Kieron" last="O'Connor">Kieron O'Connor</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire en santé mentale de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire en santé mentale de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Perodeau, Guilheme" sort="Perodeau, Guilheme" uniqKey="Perodeau G" first="Guilhème" last="Pérodeau">Guilhème Pérodeau</name><affiliation wicri:level="1"><nlm:affiliation>Département de psychoéducation et de psychologie, Université du Québec en Outaouais (UQO), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de psychoéducation et de psychologie, Université du Québec en Outaouais (UQO), Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Roberge, Pasquale" sort="Roberge, Pasquale" uniqKey="Roberge P" first="Pasquale" last="Roberge">Pasquale Roberge</name><affiliation wicri:level="1"><nlm:affiliation>Département de médecine de famille et de médecine d'urgence à l'Université de Sherbrooke, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de médecine de famille et de médecine d'urgence à l'Université de Sherbrooke, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Tannenbaum, Cara" sort="Tannenbaum, Cara" uniqKey="Tannenbaum C" first="Cara" last="Tannenbaum">Cara Tannenbaum</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Faculté de médicine, Université de Montréal, Québec, Canada; Faculté de pharmacie, Université de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Faculté de médicine, Université de Montréal, Québec, Canada; Faculté de pharmacie, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Vasiliadis, Helen Maria" sort="Vasiliadis, Helen Maria" uniqKey="Vasiliadis H" first="Helen-Maria" last="Vasiliadis">Helen-Maria Vasiliadis</name><affiliation wicri:level="1"><nlm:affiliation>Faculté de médecine de l'Université de Sherbrooke, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Faculté de médecine de l'Université de Sherbrooke, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Desrosiers, Caroline" sort="Desrosiers, Caroline" uniqKey="Desrosiers C" first="Caroline" last="Desrosiers">Caroline Desrosiers</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Cruz Santiago, Diana" sort="Cruz Santiago, Diana" uniqKey="Cruz Santiago D" first="Diana" last="Cruz-Santiago">Diana Cruz-Santiago</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de médecine familiale et de médecine d'urgence, Université de Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de médecine familiale et de médecine d'urgence, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Grenier, Sebastien" sort="Grenier, Sebastien" uniqKey="Grenier S" first="Sébastien" last="Grenier">Sébastien Grenier</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec, Canada. Electronic address: sebastien.grenier@umontreal.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author></analytic><series><title level="j">Addictive behaviors</title><idno type="eISSN">1873-6327</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Anxiety (MeSH)</term><term>Benzodiazepines (adverse effects)</term><term>Benzodiazepines (therapeutic use)</term><term>Cognitive Behavioral Therapy (methods)</term><term>Deprescriptions (MeSH)</term><term>Depression (MeSH)</term><term>Drug Tapering (methods)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Self Efficacy (MeSH)</term><term>Self-Management (MeSH)</term><term>Sleep Initiation and Maintenance Disorders (MeSH)</term><term>Social Support (MeSH)</term><term>Substance Withdrawal Syndrome (psychology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term><term>Anxiété (MeSH)</term><term>Auto-efficacité (MeSH)</term><term>Benzodiazépines (effets indésirables)</term><term>Benzodiazépines (usage thérapeutique)</term><term>Déprescriptions (MeSH)</term><term>Dépression (MeSH)</term><term>Femelle (MeSH)</term><term>Gestion de soi (MeSH)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Soutien social (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Syndrome de sevrage (psychologie)</term><term>Thérapie cognitive (méthodes)</term><term>Troubles de l'endormissement et du maintien du sommeil (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Benzodiazepines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Benzodiazepines</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Benzodiazépines</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Cognitive Behavioral Therapy</term><term>Drug Tapering</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Thérapie cognitive</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Syndrome de sevrage</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Substance Withdrawal Syndrome</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Benzodiazépines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Anxiety</term><term>Deprescriptions</term><term>Depression</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Self Efficacy</term><term>Self-Management</term><term>Sleep Initiation and Maintenance Disorders</term><term>Social Support</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Anxiété</term><term>Auto-efficacité</term><term>Déprescriptions</term><term>Dépression</term><term>Femelle</term><term>Gestion de soi</term><term>Humains</term><term>Mâle</term><term>Soutien social</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Troubles de l'endormissement et du maintien du sommeil</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Long-term benzodiazepine (BZD) use among seniors is mostly inappropriate and associated with adverse health outcomes. To prevent these consequences, withdrawal is crucial, yet knowledge is limited about what predicts BZD discontinuation. Until now, most studies have focused on sociodemographic and BZD intake factors as predictors while neglecting psychological factors. This research addresses this issue by studying how the intensity of depressive symptoms, social support satisfaction, self-perceived competence in the ability to withdraw, and overall quality of sleep predict discontinuation in long-term older consumers.</p></div><div type="abstract" xml:lang="en"><p><b>METHOD</b></p><p>Seventy-three participants aged 60 years and older were enrolled in this study. There were four time measures: before discontinuation (T1), after (T2), 3 months after (T3), and 12 months after (T4). Data were collected in the "Programme d'Aide du Succès au SEvrage" (PASSE-60+) study.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Social support satisfaction predicted discontinuation at T2 and T4. Self-perceived competence in the ability to withdraw and depressive symptoms predicted discontinuation at T4. This later prediction was counterintuitive; higher depressive symptoms at T1 were linked with higher discontinuation success. BZD intake factors (length of use and dose) were good predictors for short term discontinuation. Psychological factors were moderate predictors for short term and good predictors for long term discontinuation.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Psychological factors are good predictors of discontinuation and are better predictors than BZD intake factors of long-term discontinuation. Discontinuation programs should focus on social support and self-perceived competence to improve their efficacy. Further studies are needed to acquire a more complete picture of the psychological predictors of discontinuation success. ClinicalTrials.gov Identifier: NCT02281175.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31838367</PMID><DateCompleted><Year>2021</Year><Month>01</Month><Day>12</Day></DateCompleted><DateRevised><Year>2021</Year><Month>01</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-6327</ISSN><JournalIssue CitedMedium="Internet"><Volume>102</Volume><PubDate><Year>2020</Year><Month>03</Month></PubDate></JournalIssue><Title>Addictive behaviors</Title><ISOAbbreviation>Addict Behav</ISOAbbreviation></Journal><ArticleTitle>Psychological predictors of benzodiazepine discontinuation among older adults: Results from the PASSE 60.</ArticleTitle><Pagination><MedlinePgn>106195</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0306-4603(19)30805-6</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.addbeh.2019.106195</ELocationID><Abstract><AbstractText Label="BACKGROUND">Long-term benzodiazepine (BZD) use among seniors is mostly inappropriate and associated with adverse health outcomes. To prevent these consequences, withdrawal is crucial, yet knowledge is limited about what predicts BZD discontinuation. Until now, most studies have focused on sociodemographic and BZD intake factors as predictors while neglecting psychological factors. This research addresses this issue by studying how the intensity of depressive symptoms, social support satisfaction, self-perceived competence in the ability to withdraw, and overall quality of sleep predict discontinuation in long-term older consumers.</AbstractText><AbstractText Label="METHOD">Seventy-three participants aged 60 years and older were enrolled in this study. There were four time measures: before discontinuation (T1), after (T2), 3 months after (T3), and 12 months after (T4). Data were collected in the "Programme d'Aide du Succès au SEvrage" (PASSE-60+) study.</AbstractText><AbstractText Label="RESULTS">Social support satisfaction predicted discontinuation at T2 and T4. Self-perceived competence in the ability to withdraw and depressive symptoms predicted discontinuation at T4. This later prediction was counterintuitive; higher depressive symptoms at T1 were linked with higher discontinuation success. BZD intake factors (length of use and dose) were good predictors for short term discontinuation. Psychological factors were moderate predictors for short term and good predictors for long term discontinuation.</AbstractText><AbstractText Label="CONCLUSION">Psychological factors are good predictors of discontinuation and are better predictors than BZD intake factors of long-term discontinuation. Discontinuation programs should focus on social support and self-perceived competence to improve their efficacy. Further studies are needed to acquire a more complete picture of the psychological predictors of discontinuation success. ClinicalTrials.gov Identifier: NCT02281175.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Allary</LastName><ForeName>Arnaud</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada; Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Proulx-Tremblay</LastName><ForeName>Virginie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bélanger</LastName><ForeName>Claude</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hudon</LastName><ForeName>Carol</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>École de psychologie de l'Université Laval, Québec, Canada; Centre de recherche CERVO, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marchand</LastName><ForeName>André</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Département de psychologie, Université du Québec à Montréal (UQAM), Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Connor</LastName><ForeName>Kieron</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire en santé mentale de Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pérodeau</LastName><ForeName>Guilhème</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Département de psychoéducation et de psychologie, Université du Québec en Outaouais (UQO), Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roberge</LastName><ForeName>Pasquale</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Département de médecine de famille et de médecine d'urgence à l'Université de Sherbrooke, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tannenbaum</LastName><ForeName>Cara</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Faculté de médicine, Université de Montréal, Québec, Canada; Faculté de pharmacie, Université de Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vasiliadis</LastName><ForeName>Helen-Maria</ForeName><Initials>HM</Initials><AffiliationInfo><Affiliation>Faculté de médecine de l'Université de Sherbrooke, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Desrosiers</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cruz-Santiago</LastName><ForeName>Diana</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de médecine familiale et de médecine d'urgence, Université de Montréal, Québec, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grenier</LastName><ForeName>Sébastien</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), Québec, Canada; Département de psychologie, Université de Montréal, Québec, Canada. Electronic address: sebastien.grenier@umontreal.ca.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT02281175</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><GrantID>309810</GrantID><Acronym>CAPMC</Acronym><Agency> CIHR</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>10</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Addict Behav</MedlineTA><NlmUniqueID>7603486</NlmUniqueID><ISSNLinking>0306-4603</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>12794-10-4</RegistryNumber><NameOfSubstance UI="D001569">Benzodiazepines</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001007" MajorTopicYN="N">Anxiety</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001569" MajorTopicYN="N">Benzodiazepines</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015928" MajorTopicYN="N">Cognitive Behavioral Therapy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000069340" MajorTopicYN="Y">Deprescriptions</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003863" MajorTopicYN="Y">Depression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000084862" MajorTopicYN="N">Drug Tapering</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020377" MajorTopicYN="Y">Self Efficacy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073278" MajorTopicYN="N">Self-Management</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007319" MajorTopicYN="N">Sleep Initiation and Maintenance Disorders</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012944" MajorTopicYN="Y">Social Support</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013375" MajorTopicYN="N">Substance Withdrawal Syndrome</DescriptorName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>07</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>10</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>10</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>12</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>1</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>12</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31838367</ArticleId><ArticleId IdType="pii">S0306-4603(19)30805-6</ArticleId><ArticleId IdType="doi">10.1016/j.addbeh.2019.106195</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country><region><li>Québec</li></region><settlement><li>Montréal</li><li>Québec (ville)</li></settlement><orgName><li>Université Laval</li><li>Université du Québec à Montréal</li></orgName></list><tree><country name="Canada"><region name="Québec"><name sortKey="Allary, Arnaud" sort="Allary, Arnaud" uniqKey="Allary A" first="Arnaud" last="Allary">Arnaud Allary</name></region><name sortKey="Belanger, Claude" sort="Belanger, Claude" uniqKey="Belanger C" first="Claude" last="Bélanger">Claude Bélanger</name><name sortKey="Cruz Santiago, Diana" sort="Cruz Santiago, Diana" uniqKey="Cruz Santiago D" first="Diana" last="Cruz-Santiago">Diana Cruz-Santiago</name><name sortKey="Desrosiers, Caroline" sort="Desrosiers, Caroline" uniqKey="Desrosiers C" first="Caroline" last="Desrosiers">Caroline Desrosiers</name><name sortKey="Grenier, Sebastien" sort="Grenier, Sebastien" uniqKey="Grenier S" first="Sébastien" last="Grenier">Sébastien Grenier</name><name sortKey="Hudon, Carol" sort="Hudon, Carol" uniqKey="Hudon C" first="Carol" last="Hudon">Carol Hudon</name><name sortKey="Marchand, Andre" sort="Marchand, Andre" uniqKey="Marchand A" first="André" last="Marchand">André Marchand</name><name sortKey="O Connor, Kieron" sort="O Connor, Kieron" uniqKey="O Connor K" first="Kieron" last="O'Connor">Kieron O'Connor</name><name sortKey="Perodeau, Guilheme" sort="Perodeau, Guilheme" uniqKey="Perodeau G" first="Guilhème" last="Pérodeau">Guilhème Pérodeau</name><name sortKey="Proulx Tremblay, Virginie" sort="Proulx Tremblay, Virginie" uniqKey="Proulx Tremblay V" first="Virginie" last="Proulx-Tremblay">Virginie Proulx-Tremblay</name><name sortKey="Roberge, Pasquale" sort="Roberge, Pasquale" uniqKey="Roberge P" first="Pasquale" last="Roberge">Pasquale Roberge</name><name sortKey="Tannenbaum, Cara" sort="Tannenbaum, Cara" uniqKey="Tannenbaum C" first="Cara" last="Tannenbaum">Cara Tannenbaum</name><name sortKey="Vasiliadis, Helen Maria" sort="Vasiliadis, Helen Maria" uniqKey="Vasiliadis H" first="Helen-Maria" last="Vasiliadis">Helen-Maria Vasiliadis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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